Prognostic parameters of endometrial carcinoma.

摘要: Endometrial carcinoma is the most common malignant tumor of female genital tract in Western world. Approximately 80% cases are well- to moderately differentiated (endometrioid) adenocarcinomas, which confined uterine corpus at diagnosis, and thus can be cured. Conversely, high-grade (ie, clear cell serous) carcinomas account for only 15% 20% show marked nuclear atypia. These tumors usually invade myometrium may extend beyond uterus time hysterectomy. In addition clinical morphological differences, these 2 groups endometrial differ their pathogenesis. Whereas prognosis latter group generally poor, pathologist's role establishing outcome former crucial. Furthermore, it has become progressively apparent that both overlap some extent, making dualistic model a guideline best. Over last decades, several studies have demonstrated prognostic importance various key surgical pathological parameters, including histological type, grade, surgical-pathological stage, depth myometrial invasion, vascular cervical involvement. This review presents important factors from viewpoint, attempts clarify existing conflicts classification diagnosis tumors.