CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.

作者： ZX Xia , ZX Li , M Zhang , LM Sun , QF Zhang

DOI: 10.1016/J.YEXMP.2015.10.004

关键词: Bcl-2-associated X protein 、 Apoptosis 、 p38 mitogen-activated protein kinases 、 Cell growth 、 Cell biology 、 Cancer cell 、 Caspase 3 、 Chemistry 、 Cell migration 、 Gene knockdown

摘要: … We used the inhibitor SB203580 to suppress the phosphorylation of P38 and then knocked down CARMA3. Our results showed a reduction in the number of apoptotic cells, an increase …

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CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.

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CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.

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