Method of microwave vacuum drying spherical-shaped pellets of biological materials
作者： Robert K. Evans , Jessica Sinacola , Rebecca Lizzano , Akhilesh Bhambhani
DOI:
关键词: Pellets 、 Biological materials 、 Vacuum drying 、 Microwave 、 Spherical shape 、 Chemical engineering 、 Materials science 、 Solid surface 、 Therapeutic protein 、 Spherical shaped
摘要: Methods for preparing dried pellets of biological materials are described. The can have a substantially spherical shape and prepared by freezing droplets liquid composition desired material on solid surface followed microwave vacuum drying the frozen droplets. These methods useful having high concentration material, in particular therapeutic protein or vaccine, which faster reconstitution time than lyophilized powder cakes vials.
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