Mulga snake (Pseudechis australis) envenoming: a spectrum of myotoxicity, anticoagulant coagulopathy, haemolysis and the role of early antivenom therapy – Australian Snakebite Project (ASP-19)

作者: C. I. Johnston , S. G. A. Brown , M. A. O’Leary , B. J. Currie , R. Greenberg

DOI: 10.3109/15563650.2013.787535

关键词: CoagulopathyPoison controlContext (language use)HaemolysisMedicinePseudechis australisSurgeryVenomSnake bitesInternal medicineAntivenom

摘要: Context. Mulga snakes (Pseudechis australis) are venomous with a wide distribution in Australia. Objective. The objective of this study was to describe mulga snake envenoming and the response antivenom therapy. Materials methods. Definite bites, based on expert identification or venom-specific enzyme immunoassay, were recruited from Australian Snakebite Project. Demographics, information about bite, clinical effects, laboratory investigations treatment recorded for all patients. Blood samples collected measure serum venom concentrations pre- post-antivenom therapy using immunoassay. Results. There 17 patients definite bites. median age 37 years (6–70 years); 16 male six handlers. Thirteen had systemic non-specific symptoms (11), anticoagulant coagulopathy (10), myotoxicity (7) haemolysis (6). Antivenom given ten patients; media...

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