Significance of histopathological tumor regression after neoadjuvant chemotherapy in gastric adenocarcinomas: a summary of 480 cases.
作者： Karen Becker , Rupert Langer , Daniel Reim , Alexander Novotny , Christian Meyer zum Buschenfelde
DOI: 10.1097/SLA.0B013E318216F449
关键词: Retrospective cohort study 、 Anatomical pathology 、 Survival analysis 、 Histopathology 、 Medicine 、 Chemotherapy 、 Internal medicine 、 Proportional hazards model 、 Cancer 、 Stomach cancer 、 Pathology 、 Gastroenterology
摘要: Objective: An increasing number of patients with locally advanced gastric carcinomas (GC) are being treated with preoperative chemotherapy before surgery. Background: Histopathological tumor regression may have an important prognostic impact in addition to the UICC-TNM classification system. Methods: We evaluated the histopathological tumor regression in 480 surgical resection specimens of GC after neoadjuvant cisplatin-based chemotherapy, using an established system encompassing three tumor regression grades …
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