Microsatellite markers reveal geographic population differentiation in Trichophyton rubrum

摘要: A worldwide selection of more than 200 isolates the anthropophilic dermatophyte Trichophyton rubrum were analysed using seven microsatellite markers. Fifty-five multilocus genotypes recognized, allowing a subdivision species into two populations. Both populations reproduced strictly clonally, showed different predilection on human host (scalp vs foot) and displayed geographic differentiation. Genotypes one population originated predominantly from Africa, whilst second distribution excluding African continent. Genotypic diversity was highest in population, despite lower number strains analysed, suggesting that T. is likely to have evolved Africa. No diagnostic correlation observed between any phenotypical characteristics strains. The involvement multiple single patient detected by workers other typing methods not supported these Four developed markers may be applied for purposes.