Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease
作者： N. H. Varvel , K. Bhaskar , A. R. Patil , S. W. Pimplikar , K. Herrup
DOI: 10.1523/JNEUROSCI.2441-08.2008
关键词: Amyloid beta 、 Amyloid precursor protein secretase 、 Cell cycle 、 Mitotic cell cycle 、 Cerebral cortex 、 Amyloid precursor protein 、 Neuroscience 、 Alzheimer's disease 、 Biology 、 Genetically modified mouse
摘要: Neurons subject to degeneration in Alzheimer's disease (AD) exhibit evidence of re-entry into a mitotic cell cycle even before the development of substantial AD brain pathology. In …
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