Interchromosomal homology searches drive directional ALT telomere movement and synapsis

作者: Nam Woo Cho , Robert L. Dilley , Michael A. Lampson , Roger A. Greenberg

DOI: 10.1016/J.CELL.2014.08.030

关键词: Telomere-binding proteinRAD51BiologySynapsisHomologous chromosomeTelomereTelomeric Repeat Binding Protein 1GeneticsHomologous recombinationTelomerase

摘要: … The presence of intense ALT-like telomere clusters suggests that DSB … by synapsis and recombination between distant telomeres. To directly test this hypothesis, we visualized telomere …

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