作者: Xiaomei Wang , Na Chi , Xing Tang
DOI: 10.1016/J.EJPB.2008.07.005
关键词: Absorption (skin) 、 Microparticle 、 Nasal Absorption 、 Nasal administration 、 Pharmacology 、 Microdialysis 、 Chitosan 、 Cerebrospinal fluid 、 Chemistry 、 Pharmacokinetics
摘要: … , aiming at reducing nasal mucociliary clearance and enhancing permeation of E 2 into the nasal mucosa, and then improving the E 2 bioavailability, especially for brain targeting. …