Cardiovascular magnetic resonance T2* mapping for the assessment of cardiovascular events in hypertrophic cardiomyopathy.

作者: Mareike Gastl , Christiane Gruner , Karin Labucay , Alexander Gotschy , Jochen Von Spiczak

DOI: 10.1136/OPENHRT-2019-001152

关键词: Atrial fibrillationVentricular hypertrophyCardiologyCohortHypertrophic cardiomyopathyUnivariate analysisInternal medicineHeart failureFibrosisMagnetic resonance imagingMedicine

摘要: Background Hypertrophic cardiomyopathy (HCM) is associated with an increased risk of adverse cardiac events. Beyond classic factors, relative myocardial ischaemia and succeeding alterations, which can be detected using either contrast agents or parametric mapping in cardiovascular magnetic resonance (CMR) imaging, have shown impact on outcome HCM. CMR may help to stratify T2* mapping. Therefore, the aim present study was evaluate association values fibrosis events Methods The relationship between supraventricular, ventricular arrhythmia heart failure retrospectively assessed 91 patients HCM referred for a 1.5T MR imaging system. Fibrosis as reference added model. Patients were subdivided into groups according value quartiles. Results 47 experienced event arrhythmia, 25 atrial fibrillation/flutter 17 failure. T2*≤28.7 ms yielded no whole cohort. non-obstructive showed significant univariate analysis, but not multivariate analysis. For combined endpoint arrhythmic events, there already cohort, again only analyses. stayed strongest predictor all There Conclusions Decreased by provide small HCM, especially No information

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