Cholesterol ester formation in cultured human fibroblasts. Stimulation by oxygenated sterols.
作者： MS Brown , SE Dana , JL Goldstein
DOI: 10.1016/S0021-9258(19)41498-1
关键词: Incubation 、 Biochemistry 、 Specific activity 、 Acyltransferase 、 Enzyme 、 Reductase 、 Cholesterol 、 Coenzyme A 、 Biology 、 Reverse cholesterol transport
摘要: … - cholesterol esters was determined by thin layer chromatography (1). At zero time, the free cholesterol content (determined … specific radioactivity of the free cholesterol pool in the normal …
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sci-hub.st 参考文章(14)
Joseph L. Goldstein, Michael S. Brown, Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts COMPARISON OF CELLS FROM A NORMAL SUBJECT AND FROM A PATIENT WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA Journal of Biological Chemistry. ,vol. 249, pp. 5153- 5162 ,(1974) , 10.1016/S0021-9258(19)42341-7
Andrew A. Kandutsch, Harry W. Chen, Inhibition of Sterol Synthesis in Cultured Mouse Cells by 7α-Hydroxycholesterol, 7β-Hydroxycholesterol, and 7-Ketocholesterol Journal of Biological Chemistry. ,vol. 248, pp. 8408- 8417 ,(1973) , 10.1016/S0021-9258(19)43148-7
Andrew A. Kandutsch, Harry W. Chen, Inhibition of Sterol Synthesis in Cultured Mouse Cells by Cholesterol Derivatives Oxygenated in the Side Chain Journal of Biological Chemistry. ,vol. 249, pp. 6057- 6061 ,(1974) , 10.1016/S0021-9258(19)42218-7
DeWitt S. Goodman, Daniel Deykin, Tatsuji Shiratori, THE FORMATION OF CHOLESTEROL ESTERS WITH RAT LIVER ENZYMES. Journal of Biological Chemistry. ,vol. 239, pp. 1335- 1345 ,(1964) , 10.1016/S0021-9258(18)91319-0
Michael S. Brown, Joseph L. Goldstein, Suppression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity and Inhibition of Growth of Human Fibroblasts by 7-Ketocholesterol Journal of Biological Chemistry. ,vol. 249, pp. 7306- 7314 ,(1974) , 10.1016/S0021-9258(19)42106-6
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
M. S. Brown, J. L. Goldstein, Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity Proceedings of the National Academy of Sciences of the United States of America. ,vol. 71, pp. 788- 792 ,(1974) , 10.1073/PNAS.71.3.788
HARRY W. CHEN, ANDREW A. KANDUTSCH, CHARITY WAYMOUTH, Inhibition of cell growth by oxygenated derivatives of cholesterol Nature. ,vol. 251, pp. 419- 421 ,(1974) , 10.1038/251419A0
J. L. Goldstein, S. E. Dana, M. S. Brown, Esterification of Low Density Lipoprotein Cholesterol in Human Fibroblasts and Its Absence in Homozygous Familial Hypercholesterolemia Proceedings of the National Academy of Sciences of the United States of America. ,vol. 71, pp. 4288- 4292 ,(1974) , 10.1073/PNAS.71.11.4288
M. S. Brown, S. E. Dana, J. L. Goldstein, Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Human Fibroblasts by Lipoproteins Proceedings of the National Academy of Sciences of the United States of America. ,vol. 70, pp. 2162- 2166 ,(1973) , 10.1073/PNAS.70.7.2162