Mineral and Bone Disorders in Chronic Kidney Disease
作者： Jorge B. Cannata-Andía , Natalia Carrillo-López , Minerva Rodriguez-García , José-Vicente Torregrosa
DOI: 10.1007/978-3-642-54637-2_16
关键词: Renal function 、 Renal osteodystrophy 、 Calcium 、 Reduction (orthopedic surgery) 、 Kidney disease 、 Endocrinology 、 Strontium ranelate 、 Internal medicine 、 Medicine 、 Vitamin D and neurology 、 Bone remodeling
摘要: The key players of the CKD–MBD are calcium, phosphorus, PTH, FGF23, and vitamin D hormonal system. progressive reduction kidney function greatly modified tightly interrelated mechanisms controlling these parameters. As a result, important changes occurred in bone mineral axis leading to turnover with consequences relevant clinical outcomes, such as decrease mass increased fragility fractures vascular valvular calcification great impact cardiovascular outcomes.
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