Next-Generation Live-Cell Microarray Technologies.

作者: Mario Rothbauer , Peter Ertl

DOI: 10.1007/978-1-4939-7792-5_1

关键词: OrganismDNA microarrayCellIn vitro diagnosticScreening toolComputational biologyIn vitro cell cultureMicroarrayCell analysisComputer science

摘要: Over the last decades application of cell-based assays and in vitro cell culture systems has fundamentally transformed our understanding biological functions on a cellular organism level. The resulting ubiquitous usage today's scientific world therefore generated need for advanced diagnostic systems. This increased demand further led to development miniaturized live-cell microarrays biomedical applications including high-throughput screening tools microfluidic greatest benefit analysis is ability provide quantitative data real time with high reliability sensitivity, which are key parameters any assay. An additional advantage their inherent capability large-scale single cells, multicell populations, as well spheroids.

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