Epidermal Growth Factor Receptor Mutations in Plasma DNA Samples Predict Tumor Response in Chinese Patients With Stages IIIB to IV Non–Small-Cell Lung Cancer

作者: Hua Bai , Li Mao , Hang Shu Wang , Jun Zhao , Lu Yang

DOI: 10.1200/JCO.2008.17.3930

关键词: CarcinomaCancer researchBiomarker (medicine)Epidermal growth factor receptorMedicineLung cancerCancerTyrosine kinaseMutationGefitinibPathologyOncology

摘要: Purpose Mutations in the epidermal growth factor receptor (EGFR) kinase domain can predict tumor response to tyrosine kinase inhibitors (TKIs) in non–small-cell lung cancer (NSCLC). …

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