Role of subunit interfaces in the allosteric mechanism of hemoglobin

作者： C. Chothia , S. Wodak , J. Janin

关键词: Molecule 、 Allosteric regulation 、 Protein structure 、 Crystallography 、 Protein quaternary structure 、 Protein subunit 、 Hemoglobin 、 Stereochemistry 、 Solvent 、 Chemistry 、 Methemoglobin

摘要: … In both molecules the dimer-dimer interface is closepacked. … the stability of protein folding (9) and of protein-protein associa… of the tetramer from four subunits decreases the surface area …