Engineering the Microbiome: a Novel Approach to Immunotherapy for Allergic and Immune Diseases.

作者: Nan Shen , Jose C. Clemente

DOI: 10.1007/S11882-015-0538-9

关键词: ImmunityImmune systemBiologyFlora (microbiology)ImmunologyAllergyImmunotherapyMicrobiomeGut floraHuman gastrointestinal tract

摘要: The incidence of immune disorders is growing parallel with practices associated westernization, such as dietary changes, increased use antibiotics, or elevated rates Cesarean section. These can significantly impact the gut microbiota, collection bacteria residing in human gastrointestinal tract, and subsequently disrupt delicate balance existing between commensal flora host responses. Restoring this by modifying microbiota has thus emerged a promising therapeutic approach. Here, we discuss interaction commensals immunity, along potential different interventions on treatment for inflammatory allergic diseases.

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