Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats.

作者: Xu Zhang , Yufeng Zhao , Menghui Zhang , Xiaoyan Pang , Jia Xu

DOI: 10.1371/JOURNAL.PONE.0042529

关键词:

摘要: Berberine, a major pharmacological component of the Chinese herb Coptis chinensis, which was originally used to treat bacterial diarrhea, has recently been demonstrated to be …

参考文章(68)
Yifei Zhang, Xiaoying Li, Dajin Zou, Wei Liu, Jialin Yang, Na Zhu, Li Huo, Miao Wang, Jie Hong, Peihong Wu, Guoguang Ren, Guang Ning, Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine The Journal of Clinical Endocrinology and Metabolism. ,vol. 93, pp. 2559- 2565 ,(2008) , 10.1210/JC.2007-2404
Junling Han, Huiling Lin, Weiping Huang, Modulating gut microbiota as an anti-diabetic mechanism of berberine Medical Science Monitor. ,vol. 17, ,(2011) , 10.12659/MSM.881842
Nathalie M. Delzenne, Audrey M. Neyrinck, Fredrik Bäckhed, Patrice D. Cani, Targeting gut microbiota in obesity: effects of prebiotics and probiotics Nature Reviews Endocrinology. ,vol. 7, pp. 639- 646 ,(2011) , 10.1038/NRENDO.2011.126
Gökhan S Hotamisligil, Pascal Peraldi, Adriane Budavari, Ramsey Ellis, Morris F White, Bruce M Spiegelman, IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance Science. ,vol. 271, pp. 665- 668 ,(1996) , 10.1126/SCIENCE.271.5249.665
Libin Zhou, Xiao Wang, Li Shao, Ying Yang, Wenbin Shang, Guoyue Yuan, Boren Jiang, Fengying Li, Jingfeng Tang, Hua Jing, Mingdao Chen, Berberine Acutely Inhibits Insulin Secretion from β-Cells through 3′,5′-Cyclic Adenosine 5′-Monophosphate Signaling Pathway Endocrinology. ,vol. 149, pp. 4510- 4518 ,(2008) , 10.1210/EN.2007-1752
Yitong Liu, Haiping Hao, Hongguang Xie, Hua Lv, Changxiao Liu, Guangji Wang, Oxidative demethylenation and subsequent glucuronidation are the major metabolic pathways of berberine in rats Journal of Pharmaceutical Sciences. ,vol. 98, pp. 4391- 4401 ,(2009) , 10.1002/JPS.21721
Seong-Kyu Park, Min-Soo Kim, Seong Woon Roh, Jin-Woo Bae, Blautia stercoris sp. nov., isolated from human faeces International Journal of Systematic and Evolutionary Microbiology. ,vol. 62, pp. 776- 779 ,(2012) , 10.1099/IJS.0.031625-0
Gökhan S. Hotamisligil, Inflammation and metabolic disorders Nature. ,vol. 444, pp. 860- 867 ,(2006) , 10.1038/NATURE05485
Yann Ravussin, Omry Koren, Ayme Spor, Charles LeDuc, Roee Gutman, Jesse Stombaugh, Rob Knight, Ruth E. Ley, Rudolph L. Leibel, Responses of Gut Microbiota to Diet Composition and Weight Loss in Lean and Obese Mice Obesity. ,vol. 20, pp. 738- 747 ,(2012) , 10.1038/OBY.2011.111