Surface properties of intraocular lens materials and their influence on in vitro cell adhesion
作者： Crystal M. Cunanan , Nanine M. Tarbaux , Patricia M. Knight
DOI: 10.1016/S0886-3350(13)80409-9
关键词: Adhesion 、 Scanning electron microscope 、 Chemical engineering 、 Lens (anatomy) 、 Self-healing hydrogels 、 Cell adhesion 、 Biomaterial 、 Materials science 、 Intraocular lens 、 Trypsinization
摘要: Abstract An in vitro model to assess lens epithelial cell adhesion a variety of intraocular materials was developed. Rabbit anterior capsules Were isolated and cultured serum-containing medium. Test surfaces included poly(methyl methacrylate), two new silicones (SLM-1/UV, SLM-2/UV) hydrogels (HEMA, Lidofilcon A), polytetrafluoroethylene(PTFE). Following the application culturing cells on test surfaces, adherent were removed by trypsinization counted at eight 24 hours. The material characterized electron spectroscopy for chemical analysis scanning microscopy. captive bubble technique also used interfacial free energy. More adhered PMMA than other tested ( P 2 ) or high (>40 ergs/cm energies had lower intermediate (5 40 which exhibited highest adhesion.
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