Green Tea Polyphenol Epigallocatechin 3-Gallate, Contributes to the Degradation of DNMT3A and HDAC3 in HCT 116 Human Colon Cancer Cells
作者： Michael J Wargovich , Vondina R. Moseley , James Larry Morris , Rebecca W. Knackstedt
DOI:
关键词: Methyltransferase 、 Gene silencing 、 Histone 、 Cancer 、 Real-time polymerase chain reaction 、 Colorectal cancer 、 Cancer research 、 Epigenetics 、 Biology 、 HDAC3 、 Molecular biology
摘要: Background Colon cancer is still the second leading cause of deaths in United States. Epigenetic gene silencing involving DNA methyltransferases (DNMTs) and histone deacetylases (HDACs) play an important role progression colon cancer.
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