Synthesis and Biological Evaluation of Histone Deacetylase Inhibitor Largazole and Analogs

作者: Pravin R. Bhansali

DOI:

关键词: ChemistryStereochemistryBiological evaluationHistone deacetylase inhibitor

摘要:

参考文章(86)
Peter W. Atadja, HDAC Inhibitors and Cancer Therapy Epigenetics and Disease. ,vol. 67, pp. 175- 195 ,(2011) , 10.1007/978-3-7643-8989-5_9
Jung-Hyuck Cho, Sang-Woo Park, Soon-Kyung Kwon, Yong-Koo Kang, Chang-Hyun Oh, Synthesis of new Hydantoin-3-Acetic acid Derivatives Bulletin of The Korean Chemical Society. ,vol. 9, pp. 231- 235 ,(1988)
Masataka Hoshino, Kazuhiko Tagawa, Tomohiro Okuda, Miho Murata, Kiyomitsu Oyanagi, Nobutaka Arai, Toshio Mizutani, Ichiro Kanazawa, Erich E. Wanker, Hitoshi Okazawa, Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein. Journal of Neurochemistry. ,vol. 87, pp. 257- 267 ,(2003) , 10.1046/J.1471-4159.2003.01991.X
Jessica E. Bolden, Melissa J. Peart, Ricky W. Johnstone, Anticancer activities of histone deacetylase inhibitors Nature Reviews Drug Discovery. ,vol. 5, pp. 769- 784 ,(2006) , 10.1038/NRD2133
Karen T. Smith, Jerry L. Workman, Histone deacetylase inhibitors: Anticancer compounds The International Journal of Biochemistry & Cell Biology. ,vol. 41, pp. 21- 25 ,(2009) , 10.1016/J.BIOCEL.2008.09.008
Ana Montero, John M. Beierle, Christian A. Olsen, M. Reza Ghadiri, Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures. Journal of the American Chemical Society. ,vol. 131, pp. 3033- 3041 ,(2009) , 10.1021/JA809508F
Kevin J. Wilson, David J. Witter, Jonathan B. Grimm, Phieng Siliphaivanh, Karin M. Otte, Astrid M. Kral, Judith C. Fleming, Andreas Harsch, Julie E. Hamill, Jonathan C. Cruz, Melissa Chenard, Alexander A. Szewczak, Richard E. Middleton, Bethany L. Hughes, William K. Dahlberg, J. Paul Secrist, Thomas A. Miller, Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1). Bioorganic & Medicinal Chemistry Letters. ,vol. 18, pp. 1859- 1863 ,(2008) , 10.1016/J.BMCL.2008.02.012
Albert A. Bowers, Thomas J. Greshock, Nathan West, Guillermina Estiu, Stuart L. Schreiber, Olaf Wiest, Robert M. Williams, James E. Bradner, Synthesis and Conformation-Activity Relationships of the Peptide Isosteres of FK228 and Largazole Journal of the American Chemical Society. ,vol. 131, pp. 2900- 2905 ,(2009) , 10.1021/JA807772W
Matthew J. Bottomley, Paola Lo Surdo, Paolo Di Giovine, Agostino Cirillo, Rita Scarpelli, Federica Ferrigno, Philip Jones, Petra Neddermann, Raffaele De Francesco, Christian Steinkühler, Paola Gallinari, Andrea Carfí, Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain Journal of Biological Chemistry. ,vol. 283, pp. 26694- 26704 ,(2008) , 10.1074/JBC.M803514200
Lei Zhang, Hao Fang, Wenfang Xu, Strategies in developing promising histone deacetylase inhibitors. Medicinal Research Reviews. ,vol. 30, pp. 585- 602 ,(2010) , 10.1002/MED.20169