Pseudo-outbreak of multiresistant Pseudomonas aeruginosa in a hematology unit.
作者： Paul E. Verweij , Diana Bijl , Willem J. G. Melchers , Ben E. De Pauw , Jacques F. G. M. Meis
DOI: 10.1086/647567
关键词: Fungemia 、 Imipenem 、 Ceftazidime 、 Ciprofloxacin 、 Outbreak 、 Superinfection 、 Genotyping 、 Pseudomonas aeruginosa 、 Biology 、 Microbiology
摘要: OBJECTIVE To describe the investigation of a pseudo-outbreak multiresistant Pseudomonas aeruginosa fecal colonization in hematology unit. DESIGN Retrospective chart review; prospective environmental sampling and observation stool culture technique; genotyping by random arbitrary primer polymorphic DNA polymerase chain reaction (RAPD-PCR). SETTING An academic tertiary-care hospital. PATIENTS Between August October 1994, P resistant to imipenem, ceftazidime, ciprofloxacin, all aminoglycosides was isolated from surveillance cultures 10 neutropenic patients cared for aeruginosa, with an identical susceptibility pattern, three admitted same unit year before "outbreak." Two months outbreak, 12 healthcare workers had been added staff. RESULTS Observation techniques as performed revealed that samples were taken feces toilet. When proper technique used, not 8 previously positive cultures. also two wash basins, toilet flushing water, brush. Genotyping RAPD-PCR showed isolate water strains eight outbreak. CONCLUSIONS This emphasizes importance periodic may be necessary verify techniques.
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sci-hub.st 参考文章(19)
M K York, Bacillus species pseudobacteremia traced to contaminated gloves used in collection of blood from patients with acquired immunodeficiency syndrome. Journal of Clinical Microbiology. ,vol. 28, pp. 2114- 2116 ,(1990) , 10.1128/JCM.28.9.2114-2116.1990
J A Hoogkamp-Korstanje, J F Meis, J Kissing, J van der Laag, W J Melchers, Risk of cross-colonization and infection by Pseudomonas aeruginosa in a holiday camp for cystic fibrosis patients. Journal of Clinical Microbiology. ,vol. 33, pp. 572- 575 ,(1995) , 10.1128/JCM.33.3.572-575.1995
J J Weems, A Andremont, B J Davis, C H Tancrede, M Guiguet, A A Padhye, F Squinazi, W J Martone, Pseudoepidemic of aspergillosis after development of pulmonary infiltrates in a group of bone marrow transplant patients. Journal of Clinical Microbiology. ,vol. 25, pp. 1459- 1462 ,(1987) , 10.1128/JCM.25.8.1459-1462.1987
J Boukadida, M de Montalembert, J L Gaillard, J Gobin, F Grimont, D Girault, M Véron, P Berche, Outbreak of gut colonization by Pseudomonas aeruginosa in immunocompromised children undergoing total digestive decontamination: analysis by pulsed-field electrophoresis. Journal of Clinical Microbiology. ,vol. 29, pp. 2068- 2071 ,(1991) , 10.1128/JCM.29.9.2068-2071.1991
Paul E. Verweij, Wil B. Geven, Alex van Belkum, Jacques F. Meis, Cross-infection with Pseudomonas aeruginosa in a neonatal intensive care unit characterized by polymerase chain reaction fingerprinting. Pediatric Infectious Disease Journal. ,vol. 12, pp. 1027- 1028 ,(1993) , 10.1097/00006454-199312000-00015
RobertA Weinstein, WalterE Stamm, PSEUDOEPIDEMICS IN HOSPITAL The Lancet. ,vol. 310, pp. 862- 864 ,(1977) , 10.1016/S0140-6736(77)90793-0
Allan J. Morrison, Richard P. Wenzel, Epidemiology of Infections Due to Pseudomonas aeruginosa Clinical Infectious Diseases. ,vol. 6, ,(1984) , 10.1093/CLINIDS/6.SUPPLEMENT_3.S627
S. Heard, S. Lawrence, B. Holmes, M. Costas, A pseudo-outbreak of Pseudomonas on a special care baby unit Journal of Hospital Infection. ,vol. 16, pp. 59- 65 ,(1990) , 10.1016/0195-6701(90)90049-T
R.A. Shooter, H. Gaya, E.Mary Cooke, Parveen Kumar, Niranjana Patel, M.T. Parker, B.T. Thom, DianaR. France, FOOD AND MEDICAMENTS AS POSSIBLE SOURCES OF HOSPITAL STRAINS OF PSEUDOMONAS ÆRUGINOSA The Lancet. ,vol. 293, pp. 1227- 1229 ,(1969) , 10.1016/S0140-6736(69)92114-X
Alessandro Lechi, Enrico Arosio, Paolo Pancera, Paolo Anesi, Guido Zannini, Giuseppe Todeschini, Gianluigi Cetto, Pseudomonas septicaemia. A review of 60 cases observed in a university hospital Journal of Hospital Infection. ,vol. 5, pp. 29- 37 ,(1984) , 10.1016/0195-6701(84)90098-7