Out of Many, One: Computational Reconstruction of Mouse Skin using Single-Cell Transcriptomics
作者： James C. Chen , Angela M. Christiano
DOI: 10.1016/J.STEM.2016.09.009
关键词: Stem cell 、 Basal (phylogenetics) 、 Single cell transcriptomics 、 Cell biology 、 Mouse skin 、 Biology 、 Bioinformatics 、 Heterogeneous tissue
摘要: Mammalian skin is a complex and heterogeneous tissue with several distinct compartments stem cell populations. Joost et al. (2016) now use single-cell RNaseq to comprehensively reconstruct this complexity, revealing spatial pseudotemporal differences between transcriptional programs in common basal program
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