Airway patterning: A paradigm for restricted signalling

作者: Marysia Placzek , Helen Skaer

DOI: 10.1016/S0960-9822(99)80322-4

关键词: Signal transductionBiologyFunction (biology)RepressorCell biologySignallingFibroblast growth factorEpidermal growth factorDevelopmental biologyMitogen-activated protein kinaseGeneral Biochemistry, Genetics and Molecular BiologyGeneral Agricultural and Biological Sciences

摘要: Intercellular signalling is limited by the range of cell responsiveness, often mediated repressors. A recently identified repressor, Sprouty, inhibits MAP kinase in flies, mice and humans has a conserved function patterning airways these divergent species.

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