Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

作者: Martin Köbel , Steve E Kalloger , Niki Boyd , Steven McKinney , Erika Mehl

DOI: 10.1371/JOURNAL.PMED.0050232

关键词: Clear cellOncologyInternal medicineOvarian cancerCarcinomaDiseaseBiomarker (medicine)Serous fluidDifferential diagnosisOvarian carcinomaBiology

摘要: … , and mucinous) are associated with different natural histories, most ovarian carcinoma biomarker studies and current treatment protocols for women with this disease are not subtype …

参考文章(40)
M Anttila, V M Kosma, H Ji, X Wei-Ling, J Puolakka, M Juhola, S Saarikoski, K Syrjänen, Clinical significance of alpha-catenin, collagen IV, and Ki-67 expression in epithelial ovarian cancer. Journal of Clinical Oncology. ,vol. 16, pp. 2591- 2600 ,(1998) , 10.1200/JCO.1998.16.8.2591
Heini Lassus, Arto Leminen, Johan Lundin, Pentti Lehtovirta, Ralf Butzow, Distinct subtypes of serous ovarian carcinoma identified by p53 determination Gynecologic Oncology. ,vol. 91, pp. 504- 512 ,(2003) , 10.1016/J.YGYNO.2003.08.034
Sharon L R Kardia, David E. Misek, Samir M. Hanash, George Michailidis, Rork Kuick, Eric R. Fearon, Kerby A. Shedden, Thomas J. Giordano, Danielle M. Darrah, Kathleen R. Cho, Yali Zhai, Jeremy M G Taylor, Lora H. Ellenson, Heather Reed, Donald R. Schwartz, Rong Wu, Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Research. ,vol. 62, pp. 4722- 4729 ,(2002)
Ie-Ming Shih, Robert J. Kurman, Ovarian Tumorigenesis : A Proposed Model Based on Morphological and Molecular Genetic Analysis American Journal of Pathology. ,vol. 164, pp. 1511- 1518 ,(2004) , 10.1016/S0002-9440(10)63708-X
Karsten Münstedt, Richard von Georgi, Folker E. Franke, Correlation between MIB1-determined tumor growth fraction and incidence of tumor recurrence in early ovarian carcinomas. Cancer Investigation. ,vol. 22, pp. 185- 194 ,(2004) , 10.1081/CNV-120030206
Hans E. Geisler, John P. Geisler, Greg A. Miller, Marcia J. Geisler, Michael C. Wiemann, Zhen Zhou, William Crabtree, p21 and p53 in ovarian carcinoma: their combined staining is more valuable than either alone. Cancer. ,vol. 92, pp. 781- 786 ,(2001) , 10.1002/1097-0142(20010815)92:4<781::AID-CNCR1383>3.0.CO;2-P
Edward L. Trimble, Jane Fountain, Michael J. Birrer, Summary and discussion of session recommendations. Gynecologic Oncology. ,vol. 103, pp. 23- 25 ,(2006) , 10.1016/J.YGYNO.2006.08.022
Peng Lee, Daniel G. Rosen, Changcheng Zhu, Elvio G. Silva, Jinsong Liu, Expression of progesterone receptor is a favorable prognostic marker in ovarian cancer Gynecologic Oncology. ,vol. 96, pp. 671- 677 ,(2005) , 10.1016/J.YGYNO.2004.11.010
Steven A. Narod, Jeff Boyd, Current understanding of the epidemiology and clinical implications of BRCA1 and BRCA2 mutations for ovarian cancer. Current Opinion in Obstetrics & Gynecology. ,vol. 14, pp. 19- 26 ,(2002) , 10.1097/00001703-200202000-00004
C. Blake Gilks, Diana N. Ionescu, Steve E. Kalloger, Martin Köbel, Julie Irving, Blaise Clarke, Jennifer Santos, Nhu Le, Veronika Moravan, Kenneth Swenerton, Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma Human Pathology. ,vol. 39, pp. 1239- 1251 ,(2008) , 10.1016/J.HUMPATH.2008.01.003