Certain phenylacetic acids and derivatives

摘要: Compounds of formula (I) wherein R is hydrogen, lower alkyl, (C 3 –C 6 )cycloalkyl, hydroxy, halo, alkoxy, trifluoromethoxy, trifluoromethyl or cyano; and A biaryl, optionally substituted β-naphthyl, bicyclic heterocyclic aryl, )cycloalkyl-monocyclic carbocyclic 5 C )cycloalkane fused-monocyclic aryl; pharmaceutically acceptable salts thereof; pharmaceutically esters which are useful for the treatment COX-2 dependent disorders.