Computerized brain tomography measures compared with spontaneous and suppressed plasma cortisol levels in major depression.
作者： Ulrich Frommberger , Florian Holsboer , Sabine Schlegel , Ulrich von Bardeleben , Klaus Wiedemann
DOI: 10.1016/0306-4530(89)90019-X
关键词: Hydrocortisone 、 Dexamethasone 、 Ventricular-brain ratio 、 Dexamethasone suppression test 、 Depression (differential diagnoses) 、 Brief Psychiatric Rating Scale 、 Psychology 、 Melancholia 、 Endocrinology 、 Basal (phylogenetics) 、 Internal medicine
摘要: We determined brain density and ventricular measurements with computerized tomography (CT) in 33 depressed patients compared the results basal plasma cortisol its suppressibility by dexamethasone. Mean was positively related to elevated ratio (VBR). No association could be found between dexamethasone suppression test (DST) status VBR or any other CT parameter. Elevated levels increased VBRs were correlated total scores on Brief Psychiatric Rating Scale, Global Assessment Scale Bech-Rafaelsen Melancholia but they not significantly score Hamilton Anxiety Scale.
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