作者: Oleg N. Voloshin , R.Daniel Camerini-Otero
DOI: 10.1016/J.MOLCEL.2004.09.010
关键词: Rec A Recombinases 、 Förster resonance energy transfer 、 Computational biology 、 Biology 、 Base sequence 、 Homology (biology) 、 Recombinase 、 Genetics 、 Homologous chromosome 、 Base pair
摘要: While it is still unclear how RecA and its eukaryotic homologs conduct genome-wide homology searches, Radding colleagues report in this issue of Molecular Cell (Folta-Stogniew et al., 2004) that the latter stages homologous recognition or alignment involve base flipping (localized melting) switching (annealing) at A:T rich regions.