Synaptic complex revisited; a homologous recombinase flips and switches bases.

作者: Oleg N. Voloshin , R.Daniel Camerini-Otero

DOI: 10.1016/J.MOLCEL.2004.09.010

关键词: Rec A RecombinasesFörster resonance energy transferComputational biologyBiologyBase sequenceHomology (biology)RecombinaseGeneticsHomologous chromosomeBase pair

摘要: While it is still unclear how RecA and its eukaryotic homologs conduct genome-wide homology searches, Radding colleagues report in this issue of Molecular Cell (Folta-Stogniew et al., 2004) that the latter stages homologous recognition or alignment involve base flipping (localized melting) switching (annealing) at A:T rich regions.

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