Critical path in cardiac stem cell therapy: an update on cell delivery

作者: Winston Shim , Ashish Mehta , Philip Wong , Terrance Chua , Tian Hai Koh

DOI: 10.1016/J.JCYT.2012.11.003

关键词: Myocardial infarctionCell deliveryIntensive care medicineRegenerative medicineStem cellHeart failureStem-cell therapyInternal medicineDiseaseCardiologyMedicineTherapeutic approach

摘要: Despite optimal medical therapy, cardiovascular disease remains a leading cause of morbidity and mortality worldwide. One emerging therapeutic approach for treatment cardiomyopathies is stem cell therapy. Use cells regenerative medicine has quickly evolved over the last decade. On basis encouraging pre-clinical results, therapy developed rapidly into potentially promising ischemic heart disease, myocardial infarction congestive failure. In this review, we summarize current state-of-the-art compare collective experiences gleaned from trials using intravenous, intra-coronary intra-myocardial delivery in exacting credible benefits. We discuss implications clinical outcomes reported relation to delivered as probable destiny repair.

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