Cholesterol Oxidase and Its Applications
作者： Lata Kumari , Shamsher S. Kanwar
关键词: Cholesterol 、 Human immunodeficiency virus (HIV) 、 Biochemistry 、 Cholesterol oxidase 、 Cell 、 Disease mechanisms 、 Biology 、 Microbial enzymes 、 Flavoprotein 、 Serum cholesterol
摘要: Cholesterol oxidase (COX), a bi-functional FAD-containing microbial enzyme belongs to the family oxidoreductases. COX catalyses oxidation of cholesterol into 4-cholesten-3-one. In recent time, has received great attention due its wider use in clinical (determination serum cholesterol) laboratories practice and biocatalysis for production number steroids. been shown possess potent insecticidal activity, besides track cell cholesterol. Moreover, is also implicated manifestation some diseases bacterial (tuberculosis), viral (HIV) non-viral prion origin (Alzheimer's). These applications disease mechanisms have promoted need screening, isolation characterization newer microbes from diverse habitats as source learn more about structural functional aspects. this review, we discuss sources COX, structure important biochemical properties broad range biological functions applications.
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