作者: K. Landsteiner , J. van der Scheer
DOI: 10.1084/JEM.71.4.445
关键词: Immune sera 、 Antigen 、 Cross reactions 、 Heterologous 、 Biology 、 Mutually exclusive events 、 Antibody 、 Egg albumin 、 Genetics 、 Albumin
摘要: Experiments are presented on the cross reactions of hen egg albumin immune sera with albumins other species by means exhaustion heterologous proteins and inhibition tests. From results it can be concluded that contain multiple, qualitatively distinct antibodies. For this, two not mutually exclusive explanations come into consideration: presence in a number different, perhaps similar, complex determinants, fact, established previous results, one antigenic grouping call forth formation diverse It is inferred between kindred ascribable, general, to similarity determinant structures, distribution identical groups among related proteins.