Studies of retinoids in the prevention and treatment of cancer

作者: Frank L. Meyskens

DOI: 10.1016/S0190-9622(82)70072-6

关键词: MelanomaRetinoic acidSecondary preventionBacille Calmette GuerinVitamin a acidAdjuvantDysplasiaMedicineCancer researchCancerImmunologyDermatology

摘要: Investigation of retinoids for anticancer activity in humans, either the chemopreventive or treatment mode, has been little studied. We summarize here our ongoing investigations four different areas: (1) secondary prevention cervical dysplasia with topical application all- trans -retinoic acid; (2) adjuvant resected high-risk stage I and II malignant melanoma bacille Calmette Guerin (BCG) plus minus oral vitamin A; (3) A acid therapy cutaneous metastatic melanoma; (4) isotretinoin as an agent.

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