Protective effects of the Hemopump left ventricular assist device in experimental cardiogenic shock.

摘要: The efficacy of the new cable-driven rotating left ventricular assist device Hemopump in cardiogenic shock was examined experiments with adult sheep (n = 14; body weight 50-71 kg). Shock induced by high frequency pacing. Aortic, pulmonary, central venous and pressures as well electromagnetic measurements coronary blood flow were recorded continuously; cardiac output measured thermodilution technique. Blood samples for determination oxygen content, electrolytes lactate taken under control conditions, shock, during pump intervention at different levels speed. Vascular resistance, total myocardial consumption uptake release calculated. High pacing led to a significant decrease (from 3.8 +/- 0.8 2.2 1.6 l/min), mean aortic pressure (89.1 14.4 47.6 7.2 mmHg), (2.6 0.3 1.4 0.7 ml/min per kg), (arterial coronary-venous difference lactate: 0.27 0.26 -0.32 0.72 mmol/l). this condition resulted increase (to 2.8 0.6 65.6 13.9 perfusion 25.5 11.0 59.0 14.7), nearly normal (2.5 6.1 2.1 4.8 1.7 100 g), arterial (0.24 mmol/l).(ABSTRACT TRUNCATED AT 250 WORDS)