The Sequelae of Herpes Zoster

摘要: Background: The last 40 years was a period during which the incidence of herpes zoster appears to have increased substantially. Objective: To determine whether risk complications has changed years. Methods: automated medical records health maintenance organization were screened for diagnosis codes suggesting and potentially complicated cases zoster. predictive value calculated from sampling full-text records. Records all patients with reviewed in full. Results: Of 859 individuals who met eligibility criteria, 101 identified experienced at least 1 complication, corresponding 60-day 12%. Corrected sensitivity complication-finding strategy, estimate 14%. Risk markedly age, those older than 64 having more 6 times younger 25 (odds ratio, 8.3; 95% confidence interval, 2.5-29.3). Trigeminal distribution rash presence certain conditions associated immune compromise appeared increase risk. Conclusions: apparent not accompanied by change specific or overall population-based sample. Advanced age other waning cellular immunity may confer an experiencing course Arch Intern Med. 1997;157:1209-1213