The theranostic path to personalized nanomedicine

作者: Benjamin Theek , Larissa Y. Rizzo , Josef Ehling , Fabian Kiessling , Twan Lammers

DOI: 10.1007/S40336-014-0051-5

关键词: Targeted drug deliveryPersonalized medicineNanocarriersNanomedicineDrugNanotechnologyMedicineDrug delivery

摘要: Advances in nanotechnology and chemical engineering have led to the development of many different drug delivery systems. These 1–100(0)-nm-sized carrier materials aim increase concentrations at pathological site, while avoiding their accumulation healthy non-target tissues, thereby improving balance between efficacy toxicity systemic (chemo-)therapeutic interventions. An important advantage such nanocarrier is ease incorporating both diagnostic therapeutic entities within a single formulation, enabling them be used for theranostic purposes. We here describe basic principles using nanomaterials targeting agents sites, we discuss how nanotheranostics image-guided can personalize nanomedicine treatments.

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