MicroRNAs as a potential magic bullet in cancer

作者: Frank J Slack , Joanne B Weidhaas

DOI: 10.2217/14796694.2.1.73

关键词: Magic bulletSuppressorThree prime untranslated regionmicroRNAMedicineGeneCancerBioinformaticsDiseaseLung cancer

摘要: Genes that control cell differentiation and development are frequently mutated in human cancer. Micro (mi)RNAs small regulatory RNAs emerging as important regulators of division/differentiation cancer genes. In this review, the miRNA connection is discussed possibility using novel, but potentially powerful new therapy, involving miRNAs, to treat cancers speculated on. For example, lung major cause deaths USA, existing therapies fail disease overwhelming majority cases. The let-7 one a number ‘oncomirs’, natural tumor suppressors tissue, which may prove useful treating or enhancing current treatments for

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