Radiation chemistry comes before radiation biology
作者： Peter O'Neill , Peter Wardman
DOI: 10.1080/09553000802640401
关键词: Management science 、 Radiation chemistry 、 Radiobiology 、 Physics 、 Characterization (materials science) 、 Molecular level
摘要: Purpose: This article seeks to illustrate some contributions of radiation chemistry to radiobiology and related science, and to draw attention to examples where radiation chemistry is central to our knowledge of specific aspects. Radiation chemistry is a mature branch of radiation science which is continually evolving and finding wider applications. This is particularly apparent in the study of the roles of free radicals in biology generally, and radiation biology specifically. The chemical viewpoint helps unite the spatial and temporal …
informahealthcare.com参考文章(177)
M. Grätzel, A. Henglein, S. Taniguchi, Pulsradiolytische Beobachtungen über die Reduktion des NO3−‐Ions und über Bildung und Zerfall der persalpetrigen Säure in wäßriger Lösung Berichte der Bunsengesellschaft für physikalische Chemie. ,vol. 74, pp. 292- 298 ,(1970) , 10.1002/BBPC.19700740322
P. O'Neill, Radiation-induced damage in DNA Radiation Chemistry - Present Status and Future Trends. ,vol. 87, pp. 585- 622 ,(2001) , 10.1016/S0167-6881(01)80023-9
C. E. Smithen, B. C. Millar, E. M. Fielden, Polyfunctional radiosensitizers IV. The effect of contact time and temperature on sensitization of hypoxic Chinese hamster cells in vitro by bifunctional nitroxyl compounds. The British journal of cancer. Supplement. ,vol. 3, pp. 73- 79 ,(1978)
C. von Sonntag, Free-Radical-Induced DNA Damage and Its Repair: A Chemical Perspective ,(2005)
Peter Wardman, Clemens von Sonntag, [3] Kinetic factors that control the fate of thiyl radicals in cells Methods in Enzymology. ,vol. 251, pp. 31- 45 ,(1995) , 10.1016/0076-6879(95)51108-3
R. Docampo, R.P. Mason, C. Mottley, R.P. Muniz, Generation of free radicals induced by nifurtimox in mammalian tissues. Journal of Biological Chemistry. ,vol. 256, pp. 10930- 10933 ,(1981) , 10.1016/S0021-9258(19)68534-0
Michael Graetzel, Arnim Henglein, Setsuo Taniguchi, Pulsradiolytische Untersuchung der NO‐Oxydation und des Gleichgewichts N2O3 ⇄ NO + NO2 in wäßriger Lösung Berichte der Bunsengesellschaft für physikalische Chemie. ,vol. 74, pp. 488- 492 ,(1970) , 10.1002/BBPC.19700740513
Peter Wardman, Methods to measure the reactivity of peroxynitrite-derived oxidants toward reduced fluoresceins and rhodamines. Methods in Enzymology. ,vol. 441, pp. 261- 282 ,(2008) , 10.1016/S0076-6879(08)01214-7
Susan S Wallace, Biological consequences of free radical-damaged DNA bases1,2 1Guest Editor: Miral Dizdaroglu 2This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal. Free Radical Biology and Medicine. ,vol. 33, pp. 1- 14 ,(2002) , 10.1016/S0891-5849(02)00827-4
Peter Wardman, Electronic‐Affinic Radiosensitizers John Wiley & Sons, Inc.. pp. 295- 324 ,(2009) , 10.1002/9780470526279.CH10