Mineral status of female rats affects the absorption and organ distribution of dietary cadmium derived from edible sunflower kernels (Helianthus annuus L.).

摘要: The intake of food cadmium (Cd) in microg/day over time can increase the body burden this element. Some human populations that consume subsistence rice-based diets low calcium (Ca), iron (Fe), and zinc (Zn) are more susceptible to Cd poisoning than nutritious diets. This study determined effects marginal deficiencies these essential elements on absorption organ retention from a natural contains Cd, edible sunflower kernels (Helianthus annuus L.; SFK). Weanling female rats were fed containing 20% SFK 2x2x2 factorial design with adequate amounts Ca, Zn, Fe. Marginal Zn (11 mg/kg) Fe (13 mg/kg), (0.18 derived solely SFK. These represented 39 90% NRC requirement for rat, respectively. dietary Ca concentration (2.5 g/kg) was one-half requirement. After 5 weeks experiment, 1 g their respective extrinsically labeled 37 kBq 109Cd, by whole-body counting techniques. Rats then killed organs collected 109Cd assays. No effect treatment weight gain observed; however, when low, feeding elevated 50% (P 2.5-fold (P<0.001) those In contrast, naturally occurring provided rat's enough deter excessive alone prevent significant elevation Cd. Organ content followed same general pattern as absorption. data show nutritional readily enhance comes diet. Also, some competitors such contained foods independently minimize