作者: Francesco Fontana
DOI:
关键词: Acetonitrile 、 Dimethylformamide 、 Combinatorial chemistry 、 Active ingredient 、 Scientific method 、 Crystallization 、 Lapatinib ditosylate monohydrate 、 Materials science
摘要: Object of the present invention is a process for preparation pharmaceutical active ingredient Lapatinb ditosylate monohydrate by means an improved crystallization procedure based on dimethylformamide and acetonitrile.