Advances in neurostimulation for movement disorders.
作者： Robert E. Gross , Andres M. Lozano
DOI: 10.1080/01616412.2000.11740667
关键词: Globus pallidus 、 Thalamotomy 、 Movement disorders 、 Surgery 、 Dystonia 、 Deep brain stimulation 、 Subthalamic nucleus 、 Psychology 、 Neurostimulation 、 Physical medicine and rehabilitation 、 Essential tremor
摘要: In just 12 years since its introduction, deep brain stimulation (DBS) has become well established as a safe and effective therapy in the treatment of medically refractory movement disorders. Ventralis intermedius (Vim) DBS virtually replaced thalamotomy routine clinical essential tremor, affording relief to thousands patients who previously would not have undergone surgery, there is increasing usage Vim other tremors intention (e.g., multiple sclerosis). Subthalamic nucleus (STN) globus pallidus internus (GPi) revolutionized advanced stage Parkinson's disease, improving all cardinal disease features 'on' time without dyskinesias. Finally, various sub-cortical structures being developed tested less prevalent disorders such dystonia. Future developments this rapidly advancing area will no doubt include widening indications for relatively surgical procedure, elucidation mechanisms action electrical stimulation, technological advancements effectiveness convenience.
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