Synthesis, Characterization and Anti-diabetic activity of 1,3,5-triaryl-2-pyrazolines in acetic acid solution under Ultrasound Irradiation

作者: M. Emayavaramban , N. Santhi , C. Gopi , C. Manivannan , A. Raguraman

DOI: 10.18052/WWW.SCIPRESS.COM/ILCPA.14.172

关键词: HydrochloridePyrazolineSemicarbazideHydrazideOrganic chemistryChalconeCarbon-13 NMRChemistryUltrasound irradiationNuclear chemistrySodium hydroxide

摘要: A chalcone was prepared by the reaction of 4-methylbenzaldehyde with 4-methylacetophenone in dilute methanolic sodium hydroxide solution under ultrasonic irradiationin water bath an cleaner at room temperature. Treatment this thiosemicarbazide / semicarbazide hydrochloride benzhydrazide benzenesulphonyl hydrazide phenylhydrazine afforded corresponding 2-pyrazoline good yields. All new compounds have been characterized IR, 1 H-NMR, 13 CNMR spectral data. target were evaluated

参考文章(1)
Ragini Gupta, Neetu Gupta, Anshu Jain, Improved Synthesis of Chalcones and Pyrazolines under Ultrasonic Irradiation. ChemInform. ,vol. 41, ,(2010) , 10.1002/CHIN.201030126