One-Pot and Two-Pot Synthesis of Chalcone Based Mono and Bis-Pyrazolines
作者： Saba Farooq , Zainab Ngaini
DOI: 10.1016/J.TETLET.2019.151416
关键词: Organic chemistry 、 Pyrazoline 、 Chemistry 、 Direct reaction 、 Chalcone 、 Heterocyclic compound 、 Biochemistry 、 Drug discovery
摘要: Abstract Pyrazoline is an important heterocyclic compound in organic and pharmaceutical industry. The pyrazoline-based compounds are intensively used medicines agricultural This review to highlight various synthesis of pyrazolines namely azo-pyrazolines, bis-pyrazoline, symmetrical asymmetrical via one-pot two-pot synthetic techniques. One-pot technique unique method for direct reaction α, β-unsaturated aldehydes acetophenones with hydrazines. While more commonly reported the formation chalcone prior pyrazoline. significant field related industries.
elsevier.com
sci-hub.se 参考文章(119)
A. Raguraman, N. Santhi, Synthesis and Characterization of 1,3,5-Trisubstituted Pyrazoline Derivatives by Ultrasonic Irradiation Method and Evaluation of its Antibacterial Activity International Letters of Chemistry, Physics and Astronomy. ,vol. 39, pp. 219- 233 ,(2014) , 10.18052/WWW.SCIPRESS.COM/ILCPA.39.219
M. Emayavaramban, N. Santhi, C. Gopi, C. Manivannan, A. Raguraman, Synthesis, Characterization and Anti-diabetic activity of 1,3,5-triaryl-2-pyrazolines in acetic acid solution under Ultrasound Irradiation International Letters of Chemistry, Physics and Astronomy. ,vol. 14, pp. 172- 185 ,(2013) , 10.18052/WWW.SCIPRESS.COM/ILCPA.14.172
Vishnu Nayak Badavath, Alok Kumar Singh, Surender Singh Jadav, Nibha Mishra, Abhimanyu Dev, Barij Nayan Sinha, Venkatesan Jayaprakash, Pyrazoline carboxylates as selective MAO-B inhibitors: Synthesis and Biological screening JOURNAL OF PHARMACEUTICAL CHEMISTRY. ,vol. 2, pp. 1- 5 ,(2015) , 10.14805/JPHCHEM.2015.ART35
V. M. Patel, K. R. Desai, Eco-friendly synthesis of pyrazoline derivatives over potassium carbonate Arkivoc. ,vol. 2004, ,(2004) , 10.3998/ARK.5550190.0005.111
Ponnurengam Malliappan Sivakumar, Suresh Ganesan, Prabhawathi Veluchamy, Mukesh Doble, Novel chalcones and 1,3,5-triphenyl-2-pyrazoline derivatives as antibacterial agents Chemical Biology & Drug Design. ,vol. 76, pp. 407- 411 ,(2010) , 10.1111/J.1747-0285.2010.01020.X
William R. Browne, J. Philip Mason, Preparation and Thermal Decomposition of Selected Pyrazolines. Journal of Chemical & Engineering Data. ,vol. 11, pp. 265- 266 ,(1966) , 10.1021/JE60029A044
Suresh Kumar, Sandhya Bawa, Sushma Drabu, Rajiv Kumar, Himanshu Gupta, Biological activities of pyrazoline derivatives--a recent development. Recent Patents on Anti-infective Drug Discovery. ,vol. 4, pp. 154- 163 ,(2009) , 10.2174/157489109789318569
Evelyn Winter, Patrícia Devantier Neuenfeldt, Louise Domeneghini Chiaradia-Delatorre, Charlotte Gauthier, Rosendo Augusto Yunes, Ricardo José Nunes, Tânia Beatriz Creczynski-Pasa, Attilio Di Pietro, Symmetric bis-chalcones as a new type of breast cancer resistance protein inhibitors with a mechanism different from that of chromones. Journal of Medicinal Chemistry. ,vol. 57, pp. 2930- 2941 ,(2014) , 10.1021/JM401879Z
Badri Narayan Acharya, Deepika Saraswat, Mugdha Tiwari, Asish Kumar Shrivastava, Ramarao Ghorpade, Saroj Bapna, Mahabir Parshad Kaushik, Synthesis and antimalarial evaluation of 1, 3, 5-trisubstituted pyrazolines. European Journal of Medicinal Chemistry. ,vol. 45, pp. 430- 438 ,(2010) , 10.1016/J.EJMECH.2009.10.023
Zeba N Siddiqui, TN Mohammed Musthafa, Anis Ahmad, Asad U Khan, None, Thermal solvent-free synthesis of novel pyrazolyl chalcones and pyrazolines as potential antimicrobial agents Bioorganic & Medicinal Chemistry Letters. ,vol. 21, pp. 2860- 2865 ,(2011) , 10.1016/J.BMCL.2011.03.080