Epicardial off-pump pulmonary vein isolation and vagal denervation improve long-term outcome and quality of life in patients with atrial fibrillation

摘要: OBJECTIVES: The limited information available on thoracoscopic pulmonary vein isolation combined with ganglionated plexi ablation and the lack of studies regarding its effect quality life physical capacity urged us to study acute long-term results in patients atrial fibrillation. METHODS: Forty-three (mean age 57.1 years) symptomatic fibrillation referred for off-pump epicardial using radiofrequency energy were included. RESULTS: improved significantly at 6-month follow-up compared baseline +/- standard deviation, 165.2 65 Watt versus 155.9 57 Watt, P = .02). Quality (Short Form-36 health survey) 12 months after surgery all subscales except bodily pain. symptom severity questionnaire score decreased from mean 15.2 4.0 points 10.7 4.8 (P Overall, 25 33 (76%) followed up had no recurrences or episodes 24-hour Holter recordings. corresponding figures 79% (19/24) paroxysmal fibrillation, 100% (2/2) persistent 57% (4/7) permanent most common complication was bleeding events (9%) during dissection. CONCLUSIONS: Epicardial life, symptoms, exercise therefore may be considered who fail endocardial as a first-line procedure if left appendage exclusion is warranted.