Metabolic bone disease (anticonvulsant osteomalacia) and renal tubular acidosis in tuberous sclerosis.
作者： János P. RADÓ , Ågnes HARIS
DOI: 10.2169/INTERNALMEDICINE.32.574
关键词: Renal tubular acidosis 、 Metabolic bone disease 、 Internal medicine 、 Tuberous sclerosis 、 Gastroenterology 、 Vitamin D and neurology 、 Primidone 、 Tubulopathy 、 Osteomalacia 、 Medicine 、 Endocrinology 、 Bone disease
摘要: The characteristics triad of tuberous sclerosis-adenoma sebaceum, mental deficiency and epilepsy-associated with distal-type renal tubular acidosis was combined anticonvulsant osteomalacia in a 41-year-old woman. In addition to the specific bone lesions sclerosis, disease caused by an adverse effect drug possibly also disorder leading significant musculoskeletal disability. response calcium carbonicum 1-25-dihydroxyvitamin D therapy disability healed abnormal biochemical markers disappeared. present observation draws attention increased hazard threatening patients on chronic simultaneously suffering from diseases.(Internal Medicine 32: 574-579, 1993)
sci-hub.se 参考文章(21)
Leif Mosekilde, Flemming Melsen, Anticonvulsant Osteomalacia Determined by Quantitative Analysis of Bone Changes Acta Medica Scandinavica. ,vol. 199, pp. 349- 356 ,(2009) , 10.1111/J.0954-6820.1976.TB06747.X
ROBERT S. WEINSTEIN, GRAEME F. BRYCE, LINDA J. SAPPINGTON, DON W. KING, BRIAN B. GALLAGHER, Decreased Serum Ionized Calcium and Normal Vitamin D Metabolite Levels with Anticonvulsant Drug Treatment The Journal of Clinical Endocrinology and Metabolism. ,vol. 58, pp. 1003- 1009 ,(1984) , 10.1210/JCEM-58-6-1003
BOY FRAME, Osteomalacia: Current Concepts Annals of Internal Medicine. ,vol. 89, pp. 966- 982 ,(1978) , 10.7326/0003-4819-89-6-966
P.B. Robinson, M. Harris, W. Harvey, N. Papadogeorgakis, Reduced bone growth in rats treated with anticonvulsant drugs: A type II pseudohypoparathyroidism? Metabolic Bone Disease and Related Research. ,vol. 4, pp. 269- 275 ,(1982) , 10.1016/0221-8747(82)90038-8
Klaus Kruse, Adelheid Süss, Maria Büsse, Peter Schnelder, Monomeric serum calcitonin and bone turnover during anticonvulsant treatment and in congenital hypothyroidism. The Journal of Pediatrics. ,vol. 111, pp. 57- 63 ,(1987) , 10.1016/S0022-3476(87)80342-6
Robert A. Corradino, Diphenylhydantoin: direct inhibition of the vitamin D3-mediated calcium absorptive mechanism in organ-cultured duodenum Biochemical Pharmacology. ,vol. 25, pp. 863- 864 ,(1976) , 10.1016/0006-2952(76)90161-1
JOHN R. NIXON, GARY M. MILLER, HARUO OKAZAKI, MANUEL R. GOMEZ, Cerebral Tuberous Sclerosis: Postmortem Magnetic Resonance Imaging and Pathologic Anatomy Mayo Clinic Proceedings. ,vol. 64, pp. 305- 311 ,(1989) , 10.1016/S0025-6196(12)65250-1
CHARLES W. SHEPHERD, MANUEL R. GOMEZ, J.T. LIE, CYNTHIA S. CROWSON, Causes of death in patients with tuberous sclerosis. Mayo Clinic proceedings. ,vol. 66, pp. 792- 796 ,(1991) , 10.1016/S0025-6196(12)61196-3
WILLIAM JUBIZ, MARK R. HAUSSLER, TONI A. McCAIN, KEITH G. TOLMAN, Plasma 1,25-Dihydroxyvitamin D Levels in Patients Receiving Anticonvulsant Drugs The Journal of Clinical Endocrinology and Metabolism. ,vol. 44, pp. 617- 621 ,(1977) , 10.1210/JCEM-44-4-617
J P Osborne, Diagnosis of tuberous sclerosis. Archives of Disease in Childhood. ,vol. 63, pp. 1423- 1425 ,(1988) , 10.1136/ADC.63.12.1423