作者: Frans de Jonghe , Jan Swinkels
DOI: 10.2165/00023210-199707060-00004
关键词: Citalopram 、 Fluoxetine 、 Psychopharmacology 、 Paroxetine 、 Fluvoxamine 、 Pharmacology 、 Tolerability 、 Medicine 、 Sertraline 、 Reuptake inhibitor 、 Pharmacology (medical) 、 Psychiatry and Mental health 、 Clinical neurology
摘要: In this article, we raise the following question regarding treatment of depression with selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs) citalopram, fluoxetine, fluvoxamine, paroxetine and sertraline: are there clinically relevant differences between these SSRIs in terms their (i) pharmacodynamic pharmacokinetic (ii) clinical (i.e. efficacy, tolerability, adverse events safety) profiles?