Respiratory Pathways of Macrophages — Cellular Localization and Relation to Cidal Activity

摘要: Interest in the respiratory enzymes of macrophages centers on potential relevance products those to a principal macrophage function, i.e., microbicidal or cytocidal activity. Very extensive work has been carried out production peroxide, Superoxide anion, and hydroxyl radical by granulocytes during phagocytosis, upon other appropriate stimulation (reviewed recently Babior 1978). By comparison, evaluation situation is sketchy. Furthermore, picture somewhat more complex latter cells because their characteristics vary according state maturity lymphocyte-dependent ‘activation’ e.g. Karnovsky & Lazdins