Role of Endometrial Receptivity in Unexplained Infertility

摘要: Unexplained infertility is a diagnosis of exclusion after the standard tests for ovulation, tubal patency, and sperm have been performed. Some patients with unexplained may abnormal endometrial receptivity. Human implantation group processes which complex far from being completely understood. During time not only structural but molecular changes also occur. The “window implantation” (WOI) defined as phase in endometrium receptive to embryo. first attempt evaluate was conventional histology specific were noted based on days progesterone exposure. However, this an accurate or reliable evaluation endometrium. Ultrasound can provide limited value study receptivity regarding uterine contractility perfusion. Multiple advances identify markers achieved although it unlikely that single molecule be used clinical setting due inherent complexity overlap molecules receptors related implantation. A test using genomic technology appears promising customized microarray selected genes described important during WOI able samples are thought “receptive” regardless their histology.