Salivary immunity and lower respiratory tract infections in non-elite marathon runners
作者： Elisabet Cantó , Emma Roca , Lidia Perea , Ana Rodrigo-Troyano , Guillermo Suarez-Cuartin
DOI: 10.1371/JOURNAL.PONE.0206059
关键词: Immunity 、 Respiratory system 、 Basophil 、 Strenuous exercise 、 Respiratory tract infections 、 Lactoferrin 、 Physiology 、 Saliva 、 Respiratory tract 、 Medicine 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: Rationale Respiratory infections are common after strenuous exercise, when salivary immunity may be altered. We aim to investigate changes in a marathon and its relationship with lower respiratory tract (LRTI) healthy non-elite runners. Methods Forty seven runners (28 males 19 females) who completed the 42.195 km of 2016 Barcelona were studied. Saliva blood samples collected day before two days end race. Salivary IgA, antimicrobial proteins (lactoferrin, lysozyme) chemokines (Groα, Groβ, MCP-1) determined using ELISA kits saliva supernatant. Blood biochemistry haemogram analyzed all participants. The presence LRTI was considered those reported infectious symptoms during minimum 3 consecutive 2 weeks race. Results Eight participants (17%) presented follow-up. Higher lysozyme levels detected race compared without infection. A decrease lysozyme, Groα Groβ observed did not develop basal levels. correlated basophil counts, leukocyte counts. Conclusions LRTI runners. Changes related correlate systemic defense cells, which suggest an important role development
harvard.edu
sci-hub.se 参考文章(38)
K Arabatzis, D C Nieman, L M Johanssen, J W Lee, Infectious episodes in runners before and after the Los Angeles Marathon. Journal of Sports Medicine and Physical Fitness. ,vol. 30, pp. 316- 328 ,(1990)
Matthew Kuennen, Trevor Gillum, Tara Miller, Layla Riley, The effects of exercise, sex, and menstrual phase on salivary antimicrobial proteins. Exercise Immunology Review. ,vol. 20, pp. 23- 38 ,(2014)
Pedro Tauler, Sonia Martinez, Carlos Moreno, Pau Martínez, Antoni Aguilo, Changes in salivary hormones, immunoglobulin A, and C-reactive protein in response to ultra-endurance exercises. Applied Physiology, Nutrition, and Metabolism. ,vol. 39, pp. 560- 565 ,(2014) , 10.1139/APNM-2013-0466
Johanna K. Ihalainen, Moritz Schumann, Keijo Häkkinen, Antti A. Mero, Mucosal immunity and upper respiratory tract symptoms in recreational endurance runners. Applied Physiology, Nutrition, and Metabolism. ,vol. 41, pp. 96- 102 ,(2016) , 10.1139/APNM-2015-0242
D. C. Nieman, D. A. Henson, O. R. Fagoaga, A. C. Utter, D. M. Vinci, J. M. Davis, S. L. Nehlsen-Cannarella, Change in salivary IgA following a competitive marathon race. International Journal of Sports Medicine. ,vol. 23, pp. 69- 75 ,(2002) , 10.1055/S-2002-19375
David C Nieman, Marathon Training and Immune Function Sports Medicine. ,vol. 37, pp. 412- 415 ,(2007) , 10.2165/00007256-200737040-00036
Laurel Traeger Mackinnon, Enid Ginn, Gregory J. Seymour, Decreased salivary immunoglobulin A secretion rate after intense interval exercise in elite kayakers European Journal of Applied Physiology. ,vol. 67, pp. 180- 184 ,(1993) , 10.1007/BF00376664
Rodrigo Terra, Sílvia Amaral Gonçalves da Silva, Verônica Salerno Pinto, Patrícia Maria Lourenço Dutra, Efeito do exercício no sistema imune: resposta, adaptação e sinalização celular Revista Brasileira De Medicina Do Esporte. ,vol. 18, pp. 208- 214 ,(2012) , 10.1590/S1517-86922012000300015
Hiroyoshi Inoue, Megumi Sakai, Yasuhiko Kaida, Kozue Kaibara, Blood lactoferrin release induced by running exercise in normal volunteers: antibacterial activity Clinica Chimica Acta. ,vol. 341, pp. 165- 172 ,(2004) , 10.1016/J.CCCN.2003.12.001
VERNON NEVILLE, MICHAEL GLEESON, JONATHAN P. FOLLAND, Salivary IgA as a risk factor for upper respiratory infections in elite professional athletes. Medicine and Science in Sports and Exercise. ,vol. 40, pp. 1228- 1236 ,(2008) , 10.1249/MSS.0B013E31816BE9C3