作者: G W Hoyle , R L Hill
DOI: 10.1016/S0021-9258(18)52371-1
关键词: Intron 、 Gene 、 Exon 、 Nucleic acid sequence 、 GABBR2 、 Molecular biology 、 Biology 、 GABBR1 、 5-HT5A receptor 、 Coding region
摘要: The gene encoding the rat Kupffer cell receptor for fucose and galactose (Lehrman, M. A., Hill, R. L. (1986) J. Biol. Chem. 261, 7419-7425 Lehrman, Haltiwanger, S., 7426-7432) has been isolated characterized. nucleotide sequence of 9.7-kilobase 1 kilobase 5'-flanking was determined. 5' end coding determined by primer extension S1 mapping transcript. Knowledge transcription start site allowed potential promoter elements to be identified. is encoded seven exons that are split six introns. divisions among domains in can correlated with gene. carbohydrate recognition domain three similar those hepatic lectin, human Fc IgE, cartilage proteoglycan core protein genes. A model evolution vertebrate lectin genes have analyzed presented.