Splenectomy and preemptive interferon therapy for hepatitis C patients after living-donor liver transplantation.

摘要: Recurrent hepatitis C after liver transplantation is a major cause of graft failure. We routinely perform preemptive interferon and ribavirin therapy in patients living-donor indicated for C-related cirrhosis. One the obstacles includes blood cytopenia. To overcome this problem, we recently performed splenectomy concurrently with transplantation. Thirty-five underwent received C. They were divided into two groups: those (group A, n = 21) without B, 14). There was no significant difference frequency morbidity between groups. Platelet counts well maintained group A during therapy, cytopenia led to discontinuation one B patient. The results preliminary study warrant randomized control trial examine feasibility viral