Cardiac Resynchronization Therapy Acutely Improves Ventricular-Arterial Coupling by Reducing the Arterial Load: Assessment by Pressure-Volume Loops

摘要: arterial coupling by reducing effective elastance (Ea) on long-term follow-up. Detailed invasive studies showing possible acute peripheral effects of CRT are not available. We evaluated the hemodynamic in patients with systolic dysfunction, order to investigate impact ventriculararterial and, particular, Ea immediately after initiation pacing. Methods: studied 37 heart failure undergoing implantation based conventional criteria. On implantation, left ventricular (LV) pressure and volume data were determined via a conductance catheter. Twelve standard indication for electrophysiologic study preserved LV function served as control group. Results: In comparison group, showed reduced diastolic function. end-systolic (Ees: pressure/volume) was impaired (0.79 ± 0.33 mm Hg/mL vs 1.84 0.89 Hg/mL, P = 0.012) Ees/Ea (0.36 0.17 1.19 1.81, 0.022). patients, improved function, increasing stroke work from 3.9 1.8 L*mm Hg 6.9± 3.3 (P< 0.001) Ees 1.02 0.62 (P 0.001). decreased 2.59 1.35 1.68 0.91 < 0.001), leading an increase 0.70 0.38 Conclusion: Our indicate that switching induces immediate reduction load, conceivably consequence restored autonomic balance. (PACE 2015; 00:1‐7)